Megaloblastic Anemia Is Caused by Vitamin B12 Deficiency!

Blood is a crucial body fluid that plays an important role in many body functions. In addition, this body fluid consists of blood plasma as well as blood cells, such as leukocytes, erythrocytes, and platelets.

But, among the most important blood functions is the transportation of oxygen from lungs to other tissues in the body. Moreover, hemoglobin, i.e., a protein found in erythrocytes, is responsible for proper oxygen transportation throughout the entire body.

In case the hemoglobin concentration is greatly reduced, the person suffers from a condition known as anemia.  

However, if the anemia is triggered by a vitamin B12 deficiency, the condition is called megaloblastic anemia.

The Main Culprits of Megaloblastic Anemia:

As a result of the fact that this anemia type is caused by a vitamin deficiency, you should find out the main causes of this deficiency.

The most common causes of Vitamin B12 Deficiency are:

  • Lack of glycoprotein (It is necessary for adequate absorption of this vitamin.)
  • Vitamin B12 mal-absorption (It could be caused by celiac disease, enteritis, lymphoma, radiation, and so on.)
  • Lack of TC II (A protein that transports this vitamin to where it is supposed to.)
  • Nutrition

Here Are the Most Frequently Experienced Megaloblastic Anemia Symptoms:

  • Dizziness
  • Tiredness
  • Difficulty breathing
  • A painful tongue characterized by burning sensation
  • Pallor
  • Muscle weakness
  • Reduced appetite
  • Lowered body weight
  • Heart palpitation
  • Diarrhea
  • Tingling in legs
  • Irritability
  • Memory problems
  • Dementia
  • Depression

Note: This vitamin is typically stored in the human body for a long time, so for its proper detection, the deficiency should be present for longer period in the body.

How to Prevent and Treat This Type of Anemia:

Since vitamin B12 deficiency leads to the development of this anemia type, consider taking an adequate amount of vitamin B12.

That’s not all, you should also include foods rich in vitamin B12 in your daily diet.

For example, consume more eggs, seafood, poultry, red meat, cereals, milk, and dairy products, etc.


  • Meselson, Alec. ”The Complete Guide on Anemia”;
  • Calton, Jayson; and Calton, Mira. ”The Micronutrient Miracle”;
  • Pattison, Rossie. ”The Vitamin B12 Solution”;